Mass spectrometry analysis of protonated marine natural product seriniquinone

Citation:
da Silva, RM, Guaratini T, Jimenez PC, Fenical W, Costa-Lotufo LV, Vessecchi R, Lopes NP.  2018.  Mass spectrometry analysis of protonated marine natural product seriniquinone. Journal of the Brazilian Chemical Society. 29:1162-1166.

Date Published:

2018/05

Keywords:

atoms, cancer, chemistry, computational chemistry, density, dermcidin, drugs, electrospray ionization mass spectrometry, fragmentation, metabolism, quinones, Serinicoccus, seriniquinone

Abstract:

Seriniquinone is a natural quinone isolated from a rare marine bacterium of the genus Serinicoccus. This secondary metabolite has been shown to have anticancer properties, which has raised attention of the scientific community. In this short report, we present the first investigation of the gas-phase chemistry fragmentation reactions of seriniquinone in electrospray ionization tandem mass spectrometry (ESI-MS/MS), to be further applied in pharmacokinetics and metabolism studies. All the proposals herein were supported by computational chemistry.

Notes:

n/a

Website

DOI:

10.21577/0103-5053.20180037