Professor, Bioinformatics, Computational Biology, Genomics

Director, Scripps Genome Center

Research Interests:

  • Microbial Genome Annotation; Comparison of whole genomes in closely related organisms and identification of laterally transferred genes using comparative operon structure for gene function and assignment
  • Alternative Splicing in Eukaryotic Genes in humans, mice and rats. Impact on protein structure, emphasis on transcription factors. Impact in cancer related genes and genes expressed in embryonic development
  • Regulation of RNA; Comparative identification of microRNA genes, prediction of mRNA targets of microRNA genes, prediction of pre-mRNA targets of RNA binding proteins, reconstruction of regulatory networks for RNA expression

Degrees:

  • B.S., Computer Science and Russian, Duke University
  • M.S., Computer Science, University of Maryland, College Park: "Query Answering in Distributed Database Systems"
  • Ph.D., Computer Science, University of Maryland, College Park: "Generating Cooperative Answers in Deductive Databases"